Free recipe for a Tendon Supplements meal that is natural, effective, traditional, and tasty. If you want strong bones, tendons, and connective tissue, if you want to. Consumer Reports article claims dietary supplements put your health at risk simply because they Dietary Supplements at Dowest. Traditional formulas for relief of specific symptoms. Also offers herbal shampoos and oils. IBS Supplements for Irritable Bowel Syndrome Supplements for the dietary management of IBS can be unbelievably helpful for stabilizing digestion, especially when used. Most Effective Dietary Supplements Weight Loss PhilippinesThe Truth Behind the Top 10 Dietary Supplements. What you need to know about the most popular dietary and nutritional supplements on the market. Anabolic steroid - Wikipedia. This article is about androgens as medications. For androgens as natural hormones, see Androgen. Anabolic steroids, also known more properly as anabolic- androgenic steroids (AAS). They are anabolic and increase protein within cells, especially in skeletal muscles. AAS also have varying degrees of androgenic and virilizing effects, including induction of the development and maintenance of masculinesecondary sexual characteristics such as the growth of the vocal cords and body hair. The word anabolic, referring to anabolism, comes from the Greek . The American College of Sports Medicine acknowledges that AAS, in the presence of adequate diet, can contribute to increases in body weight, often as lean mass increases and that the gains in muscular strength achieved through high- intensity exercise and proper diet can be additionally increased by the use of AAS in some individuals. Their use is referred to as doping and banned by most major sporting bodies. For many years, AAS have been by far the most detected doping substances in IOC- accredited laboratories. Testosterone is now nearly the only androgen used for this purpose and has been shown to increase height, weight, and fat- free mass in boys with delayed puberty. These sports include bodybuilding, weightlifting, shot put and other track and field, cycling, baseball, wrestling, mixed martial arts, boxing, football, and cricket. Such use is prohibited by the rules of the governing bodies of most sports. AAS use occurs among adolescents, especially by those participating in competitive sports. INDUSTRY IN DENIAL: Health Ranger warns about the massive heavy metals poisoning problem in the dietary supplements industry. Dog dietary supplements should be an essential part of your dog's diet. Learn why, which supplements are best and what specific ailments especially apply. It has been suggested that the prevalence of use among high- school students in the U. S. Oral administration is the most convenient. Testosterone administered by mouth is rapidly absorbed, but it is largely converted to inactive metabolites, and only about 1/6 is available in active form. In order to be sufficiently active when given by mouth, testosterone derivatives are alkylated at the 1. This modification reduces the liver's ability to break down these compounds before they reach the systemic circulation. Testosterone can be administered parenterally, but it has more irregular prolonged absorption time and greater activity in muscle in enanthate, undecanoate, or cypionateester form. These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi- weekly to once every 1. A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system. In addition, because estered testosterone is dissolved in oil, intravenous injection has the potential to cause a dangerous embolism (clot) in the bloodstream. Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone- containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 1. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non- medical purposes. Studies indicate that the anabolic properties of AAS are relatively similar despite the differences in pharmacokinetic principles such as first- pass metabolism. However, the orally available forms of AAS may cause liver damage in high doses. AAS were ranked 1. Long- term steroid abusers may develop symptoms of dependence and withdrawal on discontinuation of AAS. Recreational AAS use appears to be associated with a range of potentially prolonged psychiatric effects, including dependence syndromes, mood disorders, and progression to other forms of substance abuse, but the prevalence and severity of these various effects remains poorly understood. As a result, AAS users may get misdiagnosed by a psychiatrist not told about their habit. Case reports describe both hypomania and mania, along with irritability, elation, recklessness, racing thoughts and feelings of power and invincibility that did not meet the criteria for mania/hypomania. Compared with individuals that did not use steroids, young adult males that used AAS reported greater involvement in violent behaviors even after controlling for the effects of key demographic variables, previous violent behavior, and polydrug use. The drug response was highly variable. However: 8. 4% of subjects exhibited minimal psychiatric effects, 1. The mechanism of these variable reactions could not be explained by demographic, psychological, laboratory, or physiological measures. There have been anecdotal reports of depression and suicide in teenage steroid users. A 1. 99. 2 review found that AAS may both relieve and cause depression, and that cessation or diminished use of AAS may also result in depression, but called for additional studies due to disparate data. Most of these side- effects are dose- dependent, the most common being elevated blood pressure, especially in those with pre- existing hypertension. For example, AAS may prematurely stop the lengthening of bones (premature epiphyseal fusion through increased levels of estrogen metabolites), resulting in stunted growth. Other effects include, but are not limited to, accelerated bone maturation, increased frequency and duration of erections, and premature sexual development. AAS use in adolescence is also correlated with poorer attitudes related to health. Development of breast tissue in males, a condition called gynecomastia (which is usually caused by high levels of circulating estradiol), may arise because of increased conversion of testosterone to estradiol by the enzyme aromatase. This side- effect is temporary; the size of the testicles usually returns to normal within a few weeks of discontinuing AAS use as normal production of sperm resumes. Alteration of fertility and ovarian cysts can also occur in females. The kidney damage in the bodybuilders has similarities to that seen in morbidly obese patients, but appears to be even more severe. Water- soluble peptide hormones cannot penetrate the fatty cell membrane and only indirectly affect the nucleus of target cells through their interaction with the cell. However, as fat- soluble hormones, AAS are membrane- permeable and influence the nucleus of cells by direct action. The pharmacodynamic action of AAS begin when the exogenous hormone penetrates the membrane of the target cell and binds to an androgen receptor (AR) located in the cytoplasm of that cell. From there, the compound hormone- receptor diffuses into the nucleus, where it either alters the expression of genes. It has been hypothesized that this reduction in muscle breakdown may occur through AAS inhibiting the action of other steroid hormones called glucocorticoids that promote the breakdown of muscles. Through a number of mechanisms AAS stimulate the formation of muscle cells and hence cause an increase in the size of skeletal muscles, leading to increased strength. Depending on the length of use, the side effects of the steroid can be irreversible. Processes affected include pubertal growth, sebaceous gland oil production, and sexuality (especially in fetal development). Some examples of virilizing effects are growth of the clitoris in females and the penis in male children (the adult penis size does not change due to steroids. Men may develop an enlargement of breast tissue, known as gynecomastia, testicular atrophy, and a reduced sperm count. Compounds with a high ratio of androgenic to an anabolic effects are the drug of choice in androgen- replacement therapy (e. Determination of androgenic: anabolic ratio is typically performed in animal studies, which has led to the marketing of some compounds claimed to have anabolic activity with weak androgenic effects. This disassociation is less marked in humans, where all AAS have significant androgenic effects. The VP weight is an indicator of the androgenic effect, while the LA weight is an indicator of the anabolic effect. Two or more batches of rats are castrated and given no treatment and respectively some AAS of interest. The LA/VP ratio for an AAS is calculated as the ratio of LA/VP weight gains produced by the treatment with that compound using castrated but untreated rats as baseline: (LAc,t. The LA/VP weight gain ratio from rat experiments is not unitary for testosterone (typically 0. Animal studies also found that fat mass was reduced, but most studies in humans failed to elucidate significant fat mass decrements. The effects on lean body mass have been shown to be dose- dependent. Both muscle hypertrophy and the formation of new muscle fibers have been observed. The hydration of lean mass remains unaffected by AAS use, although small increments of blood volume cannot be ruled out. After drug withdrawal, the effects fade away slowly, but may persist for more than 6. Overall, the exercise where the most significant improvements were observed is the bench press. AR agonists are antigonadotropic . By suppressing endogenous testosterone levels and effectively replacing AR signaling in the body with that of the exogenous AAS, the myotrophic- androgenic ratio would be expected to be further increased, and this hence may be yet an additional mechanism contributing to the differences in myotrophic- androgenic ratio. In addition, some AAS, such as nandrolone, are also potent progestogens, and activation of the progesterone receptor is antigonadotropic similarly to activation of the AR. Consumer Reports Attacks Dietary Supplements. By Dr. Mercola. As you may have noticed, there's an ongoing campaign aimed at regulating supplements as drugs. This would allow the drug industry to eliminate the competition of the supplement industry, thereby increasing its own profits. The primary talking point is that supplements are not regulated as drugs, so they are therefore unsafe. Strangely, prescription drugs kill many more people than car accidents — making them one of the most dangerous products on the market. Yet, the pharmaceutical agents continue lobbying for drug regulations to be enforced upon supplements to ensure our ? In the U. S., sales of dietary supplements totaled nearly $3. U. S. By the end of January, the news agency was forced to retract its report as their lab tests were proven inaccurate. Following on the heels of this debacle, Frontline aired a program focused on concerns that consumers may endanger their health by taking vitamins and supplements. Our initial story outing the glaring bias and the subsequent public outcry led to PBS Ombudsman Michael Getler doing a detailed review of the program. In conclusion, Getler admitted that vitamin supplements do not pose . I published a follow- up on Frontline's hit piece on February 2. I further clarified the issue of how supplements are regulated. Consumer Reports Joins Organized Campaign Against Supplements. Now Consumer Reports has issued a very similar report,4 again raising the nonsensical and inaccurate claim that supplements put your health at risk simply because they're not regulated as drugs. Buried in this 1. People take more drugs these days, so the death toll is likely to be far higher. Food and Drug Administration's (FDA) adverse effects reports (AER) system, pursuant to the 2. Act. Data from this reporting system shows there were 4. Adverse effects from drugs are also far more likely to be lethal. In 2. 01. 4, there was not one single death from a vitamin supplement. Adverse events from supplements are also most commonly associated with sexual enhancers, energy- boosters and weight loss formulas, not vitamins and minerals that have well- established benefits for health. Frankly, these are the types of products you can find at many gas stations. If you are buying your supplements at the same place you find powdered doughnuts and potato chips, you are likely not a very educated consumer and should reconsider your choices. Unfortunately, many of these types of products are illegally spiked with pharmaceutical drugs! If drugs are so well- regulated, how do they end up on the shelves illegally disguised as supplements? And why are we constantly spammed with emails linking to websites where you can buy all these pharmaceuticals online without a prescription? If pharmaceutical regulations were so great, you would think they would have better control of their supply chain and stop the illegal sales of their products. But, as we have found out with the tragic opioid epidemic — drug companies are more than happy to sell as many drugs as possible. After all, they are the federally approved drug dealers that leave tax- payers and family members to clean up after the wave of deaths and addictions they have caused. Regulating Supplements Like Drugs Would Not Make Them Safer. Given these kinds of statistics, wouldn't it make more sense to argue that we need much more stringent regulations on drugs? Tylenol alone kills nearly 5. NAC is used to save the lives of those poisoned. Why focus on dietary supplements when drugs clearly pose a FAR greater health hazard? There's only one reason, and that is because supplements effectively compete with drug sales. Without supplements a lot more people would be sicker, and without alternatives, they'd have no choice besides drugs. And there can be little doubt that many supplements would vanish from the market should supplements be regulated as drugs, since the drug approval process itself can cost upwards of $2 billion — a fee that cannot be recuperated when you're selling a low- cost nutrient. The only alternative would be to charge drug prices, which means any given vitamin or mineral supplement could cost hundreds or even thousands of dollars per bottle. Click Here. Probiotic Accused of Killing Preemie. The Consumer Reports story opens with a tragic and horrible description of a premature infant given probiotics (based on life- saving evidence such as that published by Cochrane Neonatal Reviews. According to Solgar, the maker of the probiotic in question, the company fully cooperated with the U. S. Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) to investigate the contamination, and . As noted by Consumer Reports, . Fungal outbreaks have been traced back to contaminated linens, bandages and tongue depressors, for example, and preemies are a high- risk group for fungal infections. So it seems odd that the fungus could not be found anywhere except in the bottles stored at the hospital itself. While the absolute source may never be known, this is an extremely rare and tragic example that is now being used as a prime example of why supplements like probiotics should be regulated as drugs. But just how does the FDA regulate drugs when it comes to contamination? They do it through a process called Current Good Manufacturing Practice regulations (CGMPs). The FDA also has CGMP regulations for dietary supplements. So whether probiotics were regulated as supplements or as drugs, the end result in this case would have been the same, as the FDA cannot guarantee that drugs are free of contaminants either. A look at the FDA's recall list. Of these products, supplements are by far the safest to consume. The article itself does not identify the experts on this panel. Nor does it report any conflicts of interest. A separate document. Lo and behold, Consumer Reports could not have put together a more biased base of . In fact, they did a poor job of covering their tracks by picking some of the most outspoken supplement- loathing pro- pharma spokespeople out there. Paul Offit was part of this panel. It seems wherever the big pharma campaign against supplements goes, Offit is there — even though his fabrications and lack of disclosure are well- documented. And, as usual, Offit did not disclose the extent of his professional and financial relationships with the pharmaceutical industry. Offit has been paid millions of dollars by Merck, a company whose reputation rivals some of the worst on the planet. His research chair at the Children's Hospital is even sponsored by Merck. Offit has also been on the board of trustees of one of the worst front groups of all times, the American Council on Science and Health (ACSH),1. DNA from a virus lethal to pigs. Why Consumer Reports would give any credibility to someone so clearly conflicted is difficult to comprehend.'Expert' Panel Filled With Documented Supplement- Loathers. Another panel member notorious for his staunch views against dietary supplements is Dr. It seems Offit and Cohen are now tag- teaming on their respective life's work to make supplements regulated as drugs, so they can be equally expensive and . As reported by Jennifer Couzin- Frankel in 2. Hardly what one would call an epidemic of crime when drug makers are regularly featured on various Top Criminals lists and keep getting fined hundreds of millions of dollars for their illegal activities. For a rundown on some of the worst of the worst, see my previous articles, . Marvin Lipman was also part of this expert panel. Lipman dangers of dietary supplements. Pharmacopeia (USP, a compendium of drug information), which is repeatedly promoted as . One 2. 01. 5 Sam's Watch article quotes Lipman as saying: 2. Click on the button below to contact them now. Click Here. I think it's really important to note that just as you have junk food with questionable and downright hazardous ingredients on the market, there are certain types of supplements that should be viewed with suspicion as they're more prone to cause adverse effects. Top offenders as I've previously described are weight loss supplements, energy- boosting preparations and muscle or sexual enhancement products. These types of products have little to do with nutrition and health, even though they're lumped together with nutritional supplements such as vitamins, minerals and antioxidants. Marcus and Grollman, Raising Awareness Against Herbal Use. Then there's Drs. Arthur Grollman and Donald Marcus, who have campaigned against the use of herbs. In a recent paper. They also disagree with the World Health Organization's (WHO) endorsement of the use of traditional herbal remedies on the premise that traditional medicine is of unproven quality. In 2. 01. 2, Marcus and Grollman also published a paper in the Archives of Internal Medicine, discussing . Some Supplements Are Best Avoided There's only one person left on Consumer Reports' expert panel and that's Philip Gregory, director of the Center for Drug Information and Evidence- Based Practice and an associate professor of pharmacy practice at Creighton University. Gregory is also an associate editor of the Journal of Evidence- Based Complementary and Alternative Medicine. Last year, Gregory published a study showing that of the 1,5. Health Canada (1,2. FDA Med. Watch (2. Overall, and conforming to what I said earlier, . Maybe Consumer Reports could trace down where these illegal pharma products are coming from rather than trying to turn all dietary supplements into drugs, seeing how drugs kill well over 1. I agree that sexual enhancers, weight loss and performance enhancers are not product categories that most reasonably health conscious people understand, and I believe you should stay away from them as you do junk food or factory- farmed meat products. Dangerous pharmaceutical products are likely to be found in those illegally disguised supplement products. To include ALL nutritional supplements into this class of .
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